OSF HealthCare is an integrated health system that was founded by The Sisters of the Third Order of St. Francis.
Headquartered in Peoria, Illinois, OSF HealthCare employs almost 24,000 Mission Partners in 159 locations, including 16 hospitals, with 2,134 licensed beds, 39 urgent care locations, and two colleges of nursing throughout Illinois and Michigan.
The OSF HealthCare physician network employs more than 2,050 primary care, specialist and advanced practice providers.

OSF HealthCare, through OSF Home Care Services, operates an extensive network of services, including eight home health agencies, eight hospice agencies including an inpatient hospice home, home infusion pharmacy and home medical equipment.
It also owns Pointcore, Inc., composed of health care-related businesses; OSF HealthCare Foundation, the philanthropic arm for the organization; and OSF Ventures, which provides investment capital for promising health care innovation startups.
The Ministry Services office in Peoria provides corporate management services, as well as direction, consultation and assistance to the administration of the health care facilities.